Kudzu and Alcohol: Is It Effective or Dangerous?

Some people use kudzu for menopause symptoms, muscle pain, measles, dysentery, stomach pain (gastritis), fever, diarrhea, thirst, neck stiffness, and to promote sweating. Other oral uses include treatment of polio myelitis, encephalitis, migraine, deafness, diabetes, and traumatic injuries. After 4 days, I have a drink, more out of habit than anything else but found that it didn’t give me any pleasure, so why bother?

  • This compound has a positive effect on the central nervous system and the brain.
  • The dose and time course effects on selected scales of positive alcohol effects and negative alcohol effects are shown in Figure 1.
  • This is precisely what was observed in the present study as kudzu’s effects were evident after a single dose within a few hours of administration.
  • You can ingest it directly, or mix it with other foods or drinks.
  • Using neuroblastoma xenografts, Li et al. [127] showed that genistein significantly decreased the expression of DNMT3b, thereby restoring CHD5-mediated inhibition of tumor growth and tumor microvessel formation.
  • Compounds called isoflavones are thought to be responsible for its potential effects.

Estrogens can decrease how quickly the body breaks down caffeine. Decreasing the breakdown of caffeine can cause jitteriness, headache, fast heartbeat, and other side effects. But kudzu isn’t as strong as the estrogen in birth control pills. Taking kudzu along with birth control pills might decrease the effectiveness of birth control pills. If you take birth control pills along with kudzu, use an additional form of birth control such as a condom.

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with KUDZU

More recently, kudzu root has made its way to Western countries as an herbal supplement. This time, the groups were given the opposite pill from the one they’d previously taken (meaning that they acted as their own control for the experiment). Again, we calculated the total units consumed for each group, and then compared the total units consumed after placebo vs those consumed after kudzu.

A standardized formulation of kudzu extract produced minimal side effects, was well-tolerated, and resulted in a modest reduction in alcohol consumption in young nontreatment-seeking heavy drinkers. Additional studies using treatment-seeking alcohol-dependent persons will be necessary to determine the usefulness of this herbal preparation in reducing alcohol use in other populations. There is some evidence that kudzu root dietary supplements may cause liver injury. One study in mice found that taking 10 mg per day of kudzu root extract for 4 weeks caused liver toxicity (15).

We treat every type of cancer, including the most important one: yours.

While kudzu root has a long history in traditional Chinese medicine, people most often use it to help treat alcohol dependence. It may also have other benefits, such as for menopausal symptoms. Kudzu for alcoholism seems to be a new and relatively safe option for those struggling. According to the research and the experiences of those that have utilized the natural ingredient, kudzu seems to ease some of the side effects and help with curbing urges to drink. It is important to follow up with your health care providers if you are having issues with alcohol consumption to see their recommendations and follow their advice.

kudzu extract for alcoholism

They reported alcohol consumption and desire to use alcohol using a wrist actigraphy device; twice weekly laboratory visits were scheduled to monitor medication adherence and adverse events. Kudzu is one of the earliest medicinal plants used in traditional Chinese medicine. It has many profound https://ecosoberhouse.com/article/kudzu-extract-and-alcohol-addiction-can-it-help-you-drink-less/ pharmacological actions, including antidipsotropic (antialcohol abuse) activity.58,59 Two of its isoflavones, daidzin and daidzein, account for this effect. It appears to act by inhibiting aldehyde dehydrogenase 2 (ALDH-2).59 A deficiency of this enzyme reduces the risk of alcohol dependence.

Is apple cider vinegar really good for me?

Hirata et al. [136] found that genistein treatment increased the expression of sFRP1 and Smad4 tumor suppressor genes through hypomethylation of H3K9 and H3K27. The upregulation of tumor suppressors p21, p16, and BTG3 was linked with H3K4 hypermethylation in cancer cells [133,137]. In contrast, reduced occupancy of SIRT1 on the p53 and FOXO3a promoters was accompanied with increased acetylation and decreased methylation of H3K9, which resulted in activation of PTEN and CYLD in prostate cancer cells [146].

As a consequence, daidzin could reduce alcohol consumption by altering monoamines that are important in central reward pathways (Rooke et al., 2000). Supporting evidence by Keung et al. (1995) has shown that the ability of structural analogs of daidzin to increase 5-HIAL accumulation is positively correlated with the compound’s alcohol-suppressing capabilities. The significance and application of this finding to other isoflavone compounds (e.g., puerarin) and to the human mitochondrial pathway system remains unknown. Regardless of the mechanism of action, the present finding that a modest, single dose of kudzu extract reduces binge drinking has profound implications as it offers a unique opportunity for early intervention for problem drinkers. As an herbal plant extract, kudzu can be made available without a prescription. While it does not completely eliminate drinking, it is clearly effective in significantly reducing intake, which offers individuals an opportunity to engage in more responsible drinking patterns.

This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

kudzu extract for alcoholism

Puerarin plays an important role in cell regulation, involving cell expression and receptor functions. Puerarin suppressed blood pressure by upregulating the hepatic Angiotensin II type I receptor (AT1) and angiotensin-converting enzyme 2 (ACE2) mRNA expression. It suppressed rennin activity in rats with the intake of 100, 200 mg/kg/day for three weeks [115].

Liked it? Join Our Crew on Patreon! Supporters Get Access To Exclusive Rides, Locations, Adventures and Fun Times Together (Did We Mention We Take Requests?)